The relationship between periodontal and endodontic disease has been a subject of speculation for many years. The Pulp and the periodontium are developmentally and functionally closely related to each other. The simultaneous existence of pulpal and periodontal disease can complicate diagnosis and treatment planning. The success of both periodontal and endodontic therapy depends on the elimination of both disease processes, whether they exist separately or as a combined lesion.

Treatment of such lesions may be simple root canal therapy with basic periodontal therapy. In certain complex cases there may be a need to undertake a regenerative or resective approach. This paper tries to bring out four such cases of endo perio lesion.

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